With the sixth mass extinction event transpiring, one of the greatest collective responsibilities of humanity is the prevention of human induced loss of biodiversity on Earth. To do this effectively, an understanding of the processes that generates and maintains diversity is vitally important. Determining species boundaries, when and how various species came into being, insights into their biology and natural history, understanding major interactions through space and time, correlates of extinctions, ect., will enable their scientific conservation. Generating such broad knowledge invariably touches many disciplines – phylogeneitcs and systematics, evolution, ecology, palaeontology, development and behaviour – a seemingly arduous process. Given the incongruity of our collective scientific focus and given that there are an estimated 5-10 million species on earth, a majority still unnamed, rapid species documentation and focusing on large groups to understand species-related dynamics is needed. Multi-dimensional analyses of lineage diversification patterns and processes, especially that of ecologically and climatically sensitive organisms, will provide this broad knowledge base needed for long term conservation of not only the species but also the processes that generates and maintains and eventually naturally extinguishes this diversity. This is what I am interested in doing, and for this, I integrate various methods. I have worked with the climatically and ecologically sensitive frogs, and to a lesser extent, the freshwater fish and small mammals; but with my colleagues and students, I am hoping to probe deeper, using the latest tools.